Varaico: Literature-Extracted Genetic Variants

SIGMAR1

169 papers

RefSeq Summary

This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular func...

Pfam Domains

ERG2_Sigma1Raa 13–129UCSCERG2 and Sigma1 receptor like protein

ERG2_Sigma1Raa 13–217UCSCERG2 and Sigma1 receptor like protein

Gene Aliases

HGNC Name

sigma non-opioid intracellular receptor 1

HGNC Previous Symbol

OPRS1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_005866.4

p.P70S

c.208C>T

Surrounding Variants

1 paper

NM_005866.4

p.H72Y

c.214C>T

1 paper

NM_005866.4

p.V73A

c.218T>C

10 papers

NM_005866.4

p.L65Q

c.194T>A

2 papers

NM_005866.4

p.D76Y

c.226G>T

1 paper

NM_005866.4

p.E77G

c.230A>G

1 paper

NM_005866.4

p.L79V

c.235C>G

6 papers

NM_005866.4

p.Q80*

c.238C>T

1 paper

NM_005866.4

p.S59C

c.176C>G

3 papers

NM_005866.4

p.W81R

c.241T>C

5 papers

NM_005866.4

p.F83L

c.247T>C

4 papers

NM_005866.4

p.F83L

c.249C>G

4 papers

NM_005866.4

p.F83L

c.249C>A