Varaico: Literature-Extracted Genetic Variants

SIGMAR1

169 papers

RefSeq Summary

This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular func...

Pfam Domains

ERG2_Sigma1Raa 13–129UCSCERG2 and Sigma1 receptor like protein

ERG2_Sigma1Raa 13–217UCSCERG2 and Sigma1 receptor like protein

Gene Aliases

HGNC Name

sigma non-opioid intracellular receptor 1

HGNC Previous Symbol

OPRS1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005866.4

p.Q44*

c.130C>T

Surrounding Variants

2 papers

NM_005866.4

p.I42R

c.125T>G

1 paper

NM_005866.4

p.E41G

c.122A>G

1 paper

NM_005866.4

p.R47Q

c.140G>A

1 paper

NM_005866.4

p.R47R

c.141G>A

1 paper

NM_005866.4

p.E40G

c.119A>G

1 paper

NM_005866.4

p.E40K

c.118G>A

1 paper

NM_005866.4

p.Q38R

c.113A>G

1 paper

NM_005866.4

p.F37delFs

c.109_110delAA

15 papers

NM_005866.4

p.G51Splc

c.151+1G>T

1 paper

NM_005866.4

p.L28R

c.83T>G

2 papers

NM_005866.4

p.V25delFs

c.73delC

2 papers

NM_005866.4

p.V25fs

c.73_74fs