Varaico: Literature-Extracted Genetic Variants

SIGMAR1

169 papers

RefSeq Summary

This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular func...

Pfam Domains

ERG2_Sigma1Raa 13–129UCSCERG2 and Sigma1 receptor like protein

ERG2_Sigma1Raa 13–217UCSCERG2 and Sigma1 receptor like protein

Gene Aliases

HGNC Name

sigma non-opioid intracellular receptor 1

HGNC Previous Symbol

OPRS1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

18 papers

NM_005866.4

p.Q2P

c.5A>C

Surrounding Variants

1 paper

NM_005866.4

p.Q2Q

c.6G>A

1 paper

NM_005866.4

p.Q2K

c.4C>A

1 paper

NM_005866.4

p.A4T

c.10G>A

3 papers

NM_005866.4

p.A4V

c.11C>T

1 paper

NM_005866.4

p.V5delFs

c.13delC

1 paper

NM_005866.4

p.V5fs

c.13_14fs

1 paper

NM_005866.4

p.R7W

c.19C>T

1 paper

NM_005866.4

p.G6insFs

c.18dupC

2 papers

NM_005866.4

p.R7delFs

c.19delG

1 paper

NM_005866.4

p.V5_R7insFs

c.14_20dup7

1 paper

NM_005866.4

p.R7fs

c.19_20fs

1 paper

NM_005866.4

p.R8fs

c.22_23fs