Varaico: Literature-Extracted Genetic Variants

Gene:SIK1
Variant:p.T703M

SIK1

131 papers

RefSeq Summary

This gene encodes a serine/threonine protein kinase that contains a ubiquitin-associated (UBA) domain. The encoded protein is a member of the adenosine monophosphate-activated kinase (AMPK) subfamily ...

Pfam Domains

Pkinaseaa 27–278UCSCProtein kinase domain
UBA_SIK3aa 306–344UCSCProtein kinase SIK3 UBA domain

Gene Aliases

HGNC Name

salt inducible kinase 1

HGNC Previous Symbol

SNF1LK

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_173354.5
p.T703M
c.2108C>T
Surrounding Variants
1 paper
NM_173354.5
p.P698L
c.2093C>T
3 papers
NM_173354.5
p.P696L
c.2087C>T
1 paper
NM_173354.5
p.G717G
c.2151C>T
1 paper
NM_173354.5
p.A687T
c.2059G>A
1 paper
NM_173354.5
p.P720L
c.2159C>T
1 paper
NM_173354.5
p.P683P
c.2049G>C
1 paper
NM_173354.5
p.P683L
c.2048C>T
1 paper
NM_173354.5
p.A682V
c.2045C>T
1 paper
NM_173354.5
p.G672S
c.2014G>A
1 paper
NM_173354.5
p.G735D
c.2204G>A
1 paper
NM_173354.5
p.A740T
c.2218G>A
1 paper
NM_173354.5
p.L741R
c.2222T>G
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