Varaico: Literature-Extracted Genetic Variants

Gene:SIK1
Variant:p.H295R

SIK1

131 papers

RefSeq Summary

This gene encodes a serine/threonine protein kinase that contains a ubiquitin-associated (UBA) domain. The encoded protein is a member of the adenosine monophosphate-activated kinase (AMPK) subfamily ...

Pfam Domains

Pkinaseaa 27–278UCSCProtein kinase domain
UBA_SIK3aa 306–344UCSCProtein kinase SIK3 UBA domain

Gene Aliases

HGNC Name

salt inducible kinase 1

HGNC Previous Symbol

SNF1LK

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_173354.5
p.H295R
c.884A>G
Surrounding Variants
1 paper
NM_173354.5
p.A294V
c.881C>T
2 papers
NM_173354.5
p.A294T
c.880G>A
1 paper
NM_173354.5
p.N300S
c.899A>G
1 paper
NM_173354.5
p.G302D
c.905G>A
1 paper
NM_173354.5
p.A288V
c.863C>T
1 paper
NM_173354.5
p.D303N
c.907G>A
3 papers
NM_173354.5
p.P287T
c.859C>A
1 paper
NM_173354.5
p.G286E
c.857G>A
1 paper
NM_173354.5
p.P285L
c.854C>T
1 paper
NM_173354.5
p.P285S
c.853C>T
1 paper
NM_173354.5
p.A308V
c.923C>T
1 paper
NM_173354.5
p.A280V
c.839C>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."