Varaico: Literature-Extracted Genetic Variants

SIN3A

240 papers

RefSeq Summary

The protein encoded by this gene is a transcriptional regulatory protein. It contains paired amphipathic helix (PAH) domains, which are important for protein-protein interactions and may mediate repre...

Pfam Domains

PAHaa 142–186UCSCPaired amphipathic helix repeat

PAHaa 323–380UCSCPaired amphipathic helix repeat

PAHaa 478–522UCSCPaired amphipathic helix repeat

Sin3_corepressaa 552–647UCSCSin3 family co-repressor

Sin3a_Caa 886–1186UCSCC-terminal domain of Sin3a protein

Gene Aliases

HGNC Name

SIN3 transcription regulator family member A

HGNC Alias Symbols

KIAA0700; DKFZP434K2235

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001145358.2

p.E925G

c.2774A>G

Surrounding Variants

1 paper

NM_001145358.2

p.E923D

c.2769G>T

1 paper

NM_001145358.2

p.E923D

c.2769G>C

1 paper

NM_001145358.2

p.R922*

c.2764C>T

1 paper

NM_001145358.2

p.E919K

c.2755G>A

1 paper

NM_001145358.2

p.R915R

c.2745G>A

3 papers

NM_001145358.2

p.R935*

c.2803C>T

1 paper

NM_001145358.2

p.E914D

c.2742A>T

1 paper

NM_001145358.2

p.E914D

c.2742A>C

2 papers

NM_001145358.2

p.K937fs

c.2809_2810fs

3 papers

NM_001145358.2

p.K937delFs

c.2809_2810delTT

1 paper

NM_001145358.2

p.R908L

c.2723G>T

1 paper

NM_001145358.2

p.R908W

c.2722C>T