Varaico: Literature-Extracted Genetic Variants

Gene:SIX6
Variant:p.T165P

SIX6

120 papers

RefSeq Summary

The protein encoded by this gene is a homeobox protein that is similar to the Drosophila 'sine oculis' gene product. This gene is found in a cluster of related genes on chromosome 14 and is thought to...

Pfam Domains

SIX1_SDaa 9–123UCSCTranscriptional regulator, SIX1, N-terminal SD domain
Homeodomainaa 129–185UCSCHomeodomain

Gene Aliases

HGNC Name

SIX homeobox 6

HGNC Previous Symbol

OPTX2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_007374.3
p.T165P
c.493A>C
Surrounding Variants
9 papers
NM_007374.3
p.T165A
c.493A>G
1 paper
NM_007374.3
p.T165I
c.494C>T
1 paper
NM_007374.3
p.L167M
c.499C>A
1 paper
NM_007374.3
p.L167V
c.499C>G
2 papers
NM_007374.3
p.Q163*
c.487C>T
1 paper
NM_007374.3
p.T168S
c.502A>T
1 paper
NM_007374.3
p.A162T
c.484G>A
1 paper
NM_007374.3
p.T168S
c.503C>G
1 paper
NM_007374.3
p.T168T
c.504C>T
1 paper
NM_007374.3
p.P169A
c.505C>G
1 paper
NM_007374.3
p.E160E
c.480G>A
1 paper
NM_007374.3
p.S156R
c.468C>A
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