src kinase associated phosphoprotein 1

SCAP1

SKAP55

src family associated phosphoprotein 1

Src kinase-associated phosphoprotein 1

Src family-associated phosphoprotein 1

Src kinase-associated phosphoprotein of 55 kDa

SKAP-55

pp55

This gene encodes a T cell adaptor protein, a class of intracellular molecules with modular domains capable of recruiting additional proteins but that exhibit no intrinsic enzymatic activity. The encoded protein contains a unique N-terminal region followed by a PH domain and C-terminal SH3 domain. Along with the adhesion and degranulation-promoting adaptor protein, the encoded protein plays a critical role in inside-out signaling by coupling T-cell antigen receptor stimulation to the activation of integrins. [provided by RefSeq, Jul 2008].

Varaico: Literature-Extracted Genetic Variants

SKAP1

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Previous Symbol