Varaico: Literature-Extracted Genetic Variants

SLCO1B1

1,357 papers

RefSeq Summary

This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous co...

Pfam Domains

OATPaa 29–621UCSCOrganic Anion Transporter Polypeptide (OATP) family

Kazal_2aa 460–506UCSCKazal-type serine protease inhibitor domain

Gene Aliases

HGNC Name

solute carrier organic anion transporter family member 1B1

HGNC Previous Symbol

SLC21A6

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_006446.5

p.E74A

c.221A>C

Surrounding Variants

2 papers

NM_006446.5

p.E74D

c.222A>C

2 papers

NM_006446.5

p.E74D

c.222A>T

23 papers

NM_006446.5

p.F73L

c.219T>A

23 papers

NM_006446.5

p.F73L

c.219T>G

1 paper

NM_006446.5

p.F73Y

c.218T>A

27 papers

NM_006446.5

p.F73L

c.217T>C

4 papers

NM_006446.5

p.G76E

c.227G>A

1 paper

NM_006446.5

p.S72N

c.215G>A

1 paper

NM_006446.5

p.G76A

c.227G>C

2 papers

NM_006446.5

p.G76V

c.227G>T

1 paper

NM_006446.5

p.S72fs

c.214_215fs

1 paper

NM_006446.5

p.G71E

c.212G>A