Varaico: Literature-Extracted Genetic Variants

SLCO1B1

1,357 papers

RefSeq Summary

This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous co...

Pfam Domains

OATPaa 29–621UCSCOrganic Anion Transporter Polypeptide (OATP) family

Kazal_2aa 460–506UCSCKazal-type serine protease inhibitor domain

Gene Aliases

HGNC Name

solute carrier organic anion transporter family member 1B1

HGNC Previous Symbol

SLC21A6

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006446.5

p.K164E

c.490A>G

Surrounding Variants

5 papers

NM_006446.5

p.C162Y

c.485G>A

1 paper

NM_006446.5

p.C162insFs

c.485_486insC

1 paper

NM_006446.5

p.G161D

c.482G>A

1 paper

NM_006446.5

p.Y169H

c.505T>C

1 paper

NM_006446.5

p.G161Splc

c.482-8C>G

1 paper

NM_006446.5

p.M170L

c.508A>C

1 paper

NM_006446.5

p.M170L

c.508A>T

2 papers

NM_006446.5

p.M170T

c.509T>C

1 paper

NM_006446.5

p.W171G

c.511T>G

1 paper

NM_006446.5

p.W171*

c.512G>A

1 paper

NM_006446.5

p.W171*

c.513G>A

1 paper

NM_006446.5

p.I172T

c.515T>C