Varaico: Literature-Extracted Genetic Variants

SLCO1B1

1,357 papers

RefSeq Summary

This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous co...

Pfam Domains

OATPaa 29–621UCSCOrganic Anion Transporter Polypeptide (OATP) family

Kazal_2aa 460–506UCSCKazal-type serine protease inhibitor domain

Gene Aliases

HGNC Name

solute carrier organic anion transporter family member 1B1

HGNC Previous Symbol

SLC21A6

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

43 papers

NM_006446.5

p.F199F

c.597C>T

Surrounding Variants

2 papers

NM_006446.5

p.A200T

c.598G>A

1 paper

NM_006446.5

p.F199fs

c.595_596fs

1 paper

NM_006446.5

p.D198A

c.593A>C

5 papers

NM_006446.5

p.K201E

c.601A>G

1 paper

NM_006446.5

p.D198G

c.593A>G

1 paper

NM_006446.5

p.F199delFs

c.596delT

1 paper

NM_006446.5

p.D198N

c.592G>A

2 papers

NM_006446.5

p.D197Y

c.589G>T

1 paper

NM_006446.5

p.G203*

c.607G>T

1 paper

NM_006446.5

p.I196V

c.586A>G

3 papers

NM_006446.5

p.G203E

c.608G>A

1 paper

NM_006446.5

p.H204Y

c.610C>T