Varaico: Literature-Extracted Genetic Variants

SLCO1B1

1,357 papers

RefSeq Summary

This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous co...

Pfam Domains

OATPaa 29–621UCSCOrganic Anion Transporter Polypeptide (OATP) family

Kazal_2aa 460–506UCSCKazal-type serine protease inhibitor domain

Gene Aliases

HGNC Name

solute carrier organic anion transporter family member 1B1

HGNC Previous Symbol

SLC21A6

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_006446.5

p.G210Splc

c.628+1G>A

Surrounding Variants

2 papers

NM_006446.5

p.G210A

c.629G>C

3 papers

NM_006446.5

p.G210V

c.629G>T

1 paper

NM_006446.5

p.L209F

c.627A>T

5 papers

NM_006446.5

p.L209L

c.625T>C

1 paper

NM_006446.5

p.L209_G210insT

c.625_629ins3

1 paper

NM_006446.5

p.Y208H

c.622T>C

1 paper

NM_006446.5

p.S205A

c.613T>G

1 paper

NM_006446.5

p.H204Y

c.610C>T

3 papers

NM_006446.5

p.G203E

c.608G>A

1 paper

NM_006446.5

p.G203*

c.607G>T

5 papers

NM_006446.5

p.K201E

c.601A>G

2 papers

NM_006446.5

p.A200T

c.598G>A