Varaico: Literature-Extracted Genetic Variants

SLCO1B1

1,357 papers

RefSeq Summary

This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous co...

Pfam Domains

OATPaa 29–621UCSCOrganic Anion Transporter Polypeptide (OATP) family

Kazal_2aa 460–506UCSCKazal-type serine protease inhibitor domain

Gene Aliases

HGNC Name

solute carrier organic anion transporter family member 1B1

HGNC Previous Symbol

SLC21A6

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006446.5

p.L337insFs

c.1009_1010dupCT

Surrounding Variants

42 papers

NM_006446.5

p.P336R

c.1007C>G

1 paper

NM_006446.5

p.P336L

c.1007C>T

1 paper

NM_006446.5

p.P336A

c.1006C>G

1 paper

NM_006446.5

p.P336S

c.1006C>T

1 paper

NM_006446.5

p.Y338D

c.1012T>G

1 paper

NM_006446.5

p.Y338fs

c.1012_1013fs

1 paper

NM_006446.5

p.Y338C

c.1013A>G

1 paper

NM_006446.5

p.Y338F

c.1013A>T

1 paper

NM_006446.5

p.Y338*

c.1014T>A

1 paper

NM_006446.5

p.Y338*

c.1014T>G

2 papers

NM_006446.5

p.T334S

c.1001C>G

1 paper

NM_006446.5

p.V339L

c.1015G>C