Varaico: Literature-Extracted Genetic Variants

SLCO1B1

1,357 papers

RefSeq Summary

This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous co...

Pfam Domains

OATPaa 29–621UCSCOrganic Anion Transporter Polypeptide (OATP) family

Kazal_2aa 460–506UCSCKazal-type serine protease inhibitor domain

Gene Aliases

HGNC Name

solute carrier organic anion transporter family member 1B1

HGNC Previous Symbol

SLC21A6

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

9 papers

NM_006446.5

p.T345M

c.1034C>T

Surrounding Variants

1 paper

NM_006446.5

p.T345insFs

c.1035dupG

1 paper

NM_006446.5

p.T345insFs

c.1034_1035insT

1 paper

NM_006446.5

p.T345_L346insFs

c.1035_1036insT

1 paper

NM_006446.5

p.L344F

c.1032G>C

1 paper

NM_006446.5

p.L344F

c.1032G>T

1 paper

NM_006446.5

p.L347V

c.1039T>G

1 paper

NM_006446.5

p.L343I

c.1027C>A

1 paper

NM_006446.5

p.M340L

c.1018A>C

1 paper

NM_006446.5

p.M340L

c.1018A>T

1 paper

NM_006446.5

p.S351S

c.1053C>T

1 paper

NM_006446.5

p.V339L

c.1015G>C

1 paper

NM_006446.5

p.Y338*

c.1014T>A