Varaico: Literature-Extracted Genetic Variants

SLCO1B1

1,357 papers

RefSeq Summary

This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous co...

Pfam Domains

OATPaa 29–621UCSCOrganic Anion Transporter Polypeptide (OATP) family

Kazal_2aa 460–506UCSCKazal-type serine protease inhibitor domain

Gene Aliases

HGNC Name

solute carrier organic anion transporter family member 1B1

HGNC Previous Symbol

SLC21A6

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006446.5

p.K361E

c.1081A>G

Surrounding Variants

1 paper

NM_006446.5

p.K361R

c.1082A>G

3 papers

NM_006446.5

p.F360L

c.1080C>A

4 papers

NM_006446.5

p.F360L

c.1080C>G

2 papers

NM_006446.5

p.F360L

c.1078T>C

5 papers

NM_006446.5

p.Y362Y

c.1086C>T

1 paper

NM_006446.5

p.V359D

c.1076T>A

1 paper

NM_006446.5

p.V359A

c.1076T>C

1 paper

NM_006446.5

p.V363I

c.1087G>A

1 paper

NM_006446.5

p.Y358*

c.1074T>A

1 paper

NM_006446.5

p.Y358*

c.1074T>G

1 paper

NM_006446.5

p.E364K

c.1090G>A

1 paper

NM_006446.5

p.E364A

c.1091A>C