Varaico: Literature-Extracted Genetic Variants

SLCO1B1

1,357 papers

RefSeq Summary

This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous co...

Pfam Domains

OATPaa 29–621UCSCOrganic Anion Transporter Polypeptide (OATP) family

Kazal_2aa 460–506UCSCKazal-type serine protease inhibitor domain

Gene Aliases

HGNC Name

solute carrier organic anion transporter family member 1B1

HGNC Previous Symbol

SLC21A6

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006446.5

p.V448E

c.1343T>A

Surrounding Variants

1 paper

NM_006446.5

p.V448M

c.1342G>A

1 paper

NM_006446.5

p.N446I

c.1337A>T

1 paper

NM_006446.5

p.P455_L456ins1

c.1365_1366insGGG

2 papers

NM_006446.5

p.Y458F

c.1373A>T

2 papers

NM_006446.5

p.C459F

c.1376G>T

1 paper

NM_006446.5

p.D462N

c.1384G>A

19 papers

NM_006446.5

p.D462G

c.1385A>G

1 paper

NM_006446.5

p.D462D

c.1386C>T

1 paper

NM_006446.5

p.C463Y

c.1388G>A

1 paper

NM_006446.5

p.C465R

c.1393T>C

1 paper

NM_006446.5

p.C465Y

c.1394G>A

2 papers

NM_006446.5

p.Q469Q

c.1407A>G