Varaico: Literature-Extracted Genetic Variants

SLCO1B1

1,357 papers

RefSeq Summary

This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous co...

Pfam Domains

OATPaa 29–621UCSCOrganic Anion Transporter Polypeptide (OATP) family

Kazal_2aa 460–506UCSCKazal-type serine protease inhibitor domain

Gene Aliases

HGNC Name

solute carrier organic anion transporter family member 1B1

HGNC Previous Symbol

SLC21A6

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_006446.5

p.G475R

c.1423G>C

Surrounding Variants

2 papers

NM_006446.5

p.G475R

c.1423G>A

1 paper

NM_006446.5

p.C474*

c.1422T>A

1 paper

NM_006446.5

p.N477S

c.1430A>G

1 paper

NM_006446.5

p.P472S

c.1414C>T

1 paper

NM_006446.5

p.G478R

c.1432G>A

1 paper

NM_006446.5

p.G478R

c.1432G>C

1 paper

NM_006446.5

p.I479M

c.1437A>G

2 papers

NM_006446.5

p.Q469Q

c.1407A>G

1 paper

NM_006446.5

p.Y481H

c.1441T>C

1 paper

NM_006446.5

p.Y481Y

c.1443C>T

1 paper

NM_006446.5

p.I482V

c.1444A>G

3 papers

NM_006446.5

p.I482M

c.1446C>G