Varaico: Literature-Extracted Genetic Variants

SLCO1B1

1,357 papers

RefSeq Summary

This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous co...

Pfam Domains

OATPaa 29–621UCSCOrganic Anion Transporter Polypeptide (OATP) family

Kazal_2aa 460–506UCSCKazal-type serine protease inhibitor domain

Gene Aliases

HGNC Name

solute carrier organic anion transporter family member 1B1

HGNC Previous Symbol

SLC21A6

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

6 papers

NM_006446.5

p.C485F

c.1454G>T

Surrounding Variants

1 paper

NM_006446.5

p.C485*

c.1455T>A

3 papers

NM_006446.5

p.P484H

c.1451C>A

1 paper

NM_006446.5

p.L486P

c.1457T>C

1 paper

NM_006446.5

p.P484S

c.1450C>T

1 paper

NM_006446.5

p.A487_G488insFs

c.1461_1462insA

1 paper

NM_006446.5

p.A487V

c.1460C>T

3 papers

NM_006446.5

p.I482M

c.1446C>G

1 paper

NM_006446.5

p.G488S

c.1462G>A

49 papers

NM_006446.5

p.G488A

c.1463G>C

2 papers

NM_006446.5

p.G488V

c.1463G>T

1 paper

NM_006446.5

p.I482V

c.1444A>G

1 paper

NM_006446.5

p.Y481Y

c.1443C>T