Varaico: Literature-Extracted Genetic Variants

SLCO1B1

1,357 papers

RefSeq Summary

This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous co...

Pfam Domains

OATPaa 29–621UCSCOrganic Anion Transporter Polypeptide (OATP) family

Kazal_2aa 460–506UCSCKazal-type serine protease inhibitor domain

Gene Aliases

HGNC Name

solute carrier organic anion transporter family member 1B1

HGNC Previous Symbol

SLC21A6

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006446.5

p.C489S

c.1466G>C

Surrounding Variants

1 paper

NM_006446.5

p.C489S

c.1465T>A

49 papers

NM_006446.5

p.G488A

c.1463G>C

2 papers

NM_006446.5

p.G488V

c.1463G>T

1 paper

NM_006446.5

p.G488S

c.1462G>A

1 paper

NM_006446.5

p.A487_G488insFs

c.1461_1462insA

1 paper

NM_006446.5

p.A487V

c.1460C>T

1 paper

NM_006446.5

p.S492delFs

c.1474delT

1 paper

NM_006446.5

p.S492T

c.1474T>A

1 paper

NM_006446.5

p.S492insFs

c.1475dupC

1 paper

NM_006446.5

p.S492fs

c.1474_1475fs

1 paper

NM_006446.5

p.S492*

c.1475C>A

1 paper

NM_006446.5

p.L486P

c.1457T>C