Varaico: Literature-Extracted Genetic Variants

SLCO1B1

1,357 papers

RefSeq Summary

This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous co...

Pfam Domains

OATPaa 29–621UCSCOrganic Anion Transporter Polypeptide (OATP) family

Kazal_2aa 460–506UCSCKazal-type serine protease inhibitor domain

Gene Aliases

HGNC Name

solute carrier organic anion transporter family member 1B1

HGNC Previous Symbol

SLC21A6

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

4 papers

NM_006446.5

p.H575L

c.1724A>T

Surrounding Variants

1 paper

NM_006446.5

p.H575Y

c.1723C>T

1 paper

NM_006446.5

p.S576A

c.1726T>G

1 paper

NM_006446.5

p.S576*

c.1727C>A

1 paper

NM_006446.5

p.S576*

c.1727C>G

1 paper

NM_006446.5

p.M577L

c.1729A>C

1 paper

NM_006446.5

p.M577V

c.1729A>G

1 paper

NM_006446.5

p.M577L

c.1729A>T

1 paper

NM_006446.5

p.V578I

c.1732G>A

37 papers

NM_006446.5

p.R580*

c.1738C>T

3 papers

NM_006446.5

p.R580Q

c.1739G>A

1 paper

NM_006446.5

p.S569*

c.1706C>A

1 paper

NM_006446.5

p.S569*

c.1706C>G