Varaico: Literature-Extracted Genetic Variants

SLCO1B1

1,357 papers

RefSeq Summary

This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous co...

Pfam Domains

OATPaa 29–621UCSCOrganic Anion Transporter Polypeptide (OATP) family

Kazal_2aa 460–506UCSCKazal-type serine protease inhibitor domain

Gene Aliases

HGNC Name

solute carrier organic anion transporter family member 1B1

HGNC Previous Symbol

SLC21A6

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006446.5

p.K649R

c.1946A>G

Surrounding Variants

1 paper

NM_006446.5

p.K650Q

c.1948A>C

1 paper

NM_006446.5

p.K650R

c.1949A>G

1 paper

NM_006446.5

p.Y645F

c.1934A>T

1 paper

NM_006446.5

p.K654delFs

c.1962delA

49 papers

NM_006446.5

p.L643F

c.1929A>C

35 papers

NM_006446.5

p.L643F

c.1929A>T

1 paper

NM_006446.5

p.D655N

c.1963G>A

1 paper

NM_006446.5

p.D655Y

c.1963G>T

1 paper

NM_006446.5

p.D655fs

c.1963_1964fs

24 papers

NM_006446.5

p.D655G

c.1964A>G

2 papers

NM_006446.5

p.L643*

c.1928T>A

2 papers

NM_006446.5

p.L643*

c.1928T>G