Varaico: Literature-Extracted Genetic Variants

SLCO1B3

456 papers

RefSeq Summary

This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of endogenous and xenobio...

Pfam Domains

OATPaa 29–621UCSCOrganic Anion Transporter Polypeptide (OATP) family

Kazal_2aa 460–506UCSCKazal-type serine protease inhibitor domain

Gene Aliases

HGNC Name

solute carrier organic anion transporter family member 1B3

HGNC Previous Symbol

SLC21A8

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_019844.4

p.R181S

c.541C>A

Surrounding Variants

1 paper

NM_019844.4

p.R181C

c.541C>T

4 papers

NM_019844.4

p.R181H

c.542G>A

1 paper

NM_019844.4

p.N178D

c.532A>G

1 paper

NM_019844.4

p.G184R

c.550G>A

1 paper

NM_019844.4

p.G184G

c.552G>C

1 paper

NM_019844.4

p.E185K

c.553G>A

1 paper

NM_019844.4

p.T186N

c.557C>A

1 paper

NM_019844.4

p.P187T

c.559C>A

29 papers

NM_019844.4

p.V174A

c.521T>C

1 paper

NM_019844.4

p.I188T

c.563T>C

1 paper

NM_019844.4

p.I188M

c.564A>G

1 paper

NM_019844.4

p.I172I

c.516C>A