Varaico: Literature-Extracted Genetic Variants

SLCO1B3

456 papers

RefSeq Summary

This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of endogenous and xenobio...

Pfam Domains

OATPaa 29–621UCSCOrganic Anion Transporter Polypeptide (OATP) family

Kazal_2aa 460–506UCSCKazal-type serine protease inhibitor domain

Gene Aliases

HGNC Name

solute carrier organic anion transporter family member 1B3

HGNC Previous Symbol

SLC21A8

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_019844.4

p.N528D

c.1582A>G

Surrounding Variants

1 paper

NM_019844.4

p.T529A

c.1585A>G

1 paper

NM_019844.4

p.C530S

c.1588T>A

1 paper

NM_019844.4

p.C530S

c.1589G>C

1 paper

NM_019844.4

p.T531T

c.1593A>G

1 paper

NM_019844.4

p.R532G

c.1594A>G

1 paper

NM_019844.4

p.G522S

c.1564G>A

26 papers

NM_019844.4

p.G522C

c.1564G>T

1 paper

NM_019844.4

p.F535Y

c.1604T>A

11 papers

NM_019844.4

p.H520P

c.1559A>C

1 paper

NM_019844.4

p.I536F

c.1606A>T

6 papers

NM_019844.4

p.A519A

c.1557A>G

2 papers

NM_019844.4

p.Y537F

c.1610A>T