Varaico: Literature-Extracted Genetic Variants

SLCO1B3

456 papers

RefSeq Summary

This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of endogenous and xenobio...

Pfam Domains

OATPaa 29–621UCSCOrganic Anion Transporter Polypeptide (OATP) family

Kazal_2aa 460–506UCSCKazal-type serine protease inhibitor domain

Gene Aliases

HGNC Name

solute carrier organic anion transporter family member 1B3

HGNC Previous Symbol

SLC21A8

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_019844.4

p.I543L

c.1627A>C

Surrounding Variants

1 paper

NM_019844.4

p.I543L

c.1627A>T

3 papers

NM_019844.4

p.I543R

c.1628T>G

2 papers

NM_019844.4

p.V542I

c.1624G>A

1 paper

NM_019844.4

p.S545T

c.1633T>A

1 paper

NM_019844.4

p.S545A

c.1633T>G

1 paper

NM_019844.4

p.S545F

c.1634C>T

1 paper

NM_019844.4

p.L546F

c.1638G>C

1 paper

NM_019844.4

p.L546F

c.1638G>T

1 paper

NM_019844.4

p.V538V

c.1614T>C

2 papers

NM_019844.4

p.Y537F

c.1610A>T

1 paper

NM_019844.4

p.I536F

c.1606A>T

1 paper

NM_019844.4

p.F535Y

c.1604T>A