Varaico: Literature-Extracted Genetic Variants

SLCO1B3

456 papers

RefSeq Summary

This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of endogenous and xenobio...

Pfam Domains

OATPaa 29–621UCSCOrganic Anion Transporter Polypeptide (OATP) family

Kazal_2aa 460–506UCSCKazal-type serine protease inhibitor domain

Gene Aliases

HGNC Name

solute carrier organic anion transporter family member 1B3

HGNC Previous Symbol

SLC21A8

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_019844.4

p.A571G

c.1712C>G

Surrounding Variants

1 paper

NM_019844.4

p.M572V

c.1714A>G

1 paper

NM_019844.4

p.A569E

c.1706C>A

1 paper

NM_019844.4

p.F574S

c.1721T>C

1 paper

NM_019844.4

p.Q575*

c.1723C>T

2 papers

NM_019844.4

p.R580G

c.1738A>G

2 papers

NM_019844.4

p.R580*

c.1738A>T

2 papers

NM_019844.4

p.R580K

c.1739G>A

15 papers

NM_019844.4

p.G583Splc

c.1747+1G>A

1 paper

NM_019844.4

p.K561Splc

c.1683-21T>A

5 papers

NM_019844.4

p.G583E

c.1748G>A

1 paper

NM_019844.4

p.G584A

c.1751G>C

1 paper

NM_019844.4

p.P588A

c.1762C>G