Varaico: Literature-Extracted Genetic Variants

SLIT3

166 papers

RefSeq Summary

The protein encoded by this gene is secreted, likely interacting with roundabout homolog receptors to effect cell migration. Two transcript variants encoding different isoforms have been found for thi...

Pfam Domains

LRRNTaa 33–60UCSCLeucine rich repeat N-terminal domain

LRR_8aa 61–121UCSCLeucine rich repeat

LRR_8aa 109–169UCSCLeucine rich repeat

LRR_8aa 157–217UCSCLeucine rich repeat

LRRCTaa 239–264UCSCLeucine rich repeat C-terminal domain

LRRNTaa 279–306UCSCLeucine rich repeat N-terminal domain

Gene Aliases

HGNC Name

slit guidance ligand 3

HGNC Previous Symbol

SLIL2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003062.4

p.R313C

c.937C>T

Surrounding Variants

1 paper

NM_003062.4

p.K334K

c.1002G>A

1 paper

NM_003062.4

p.K340R

c.1019A>G

1 paper

NM_003062.4

p.N341N

c.1023T>C

1 paper

NM_003062.4

p.A347G

c.1040C>G

5 papers

NM_003062.4

p.V371A

c.1112T>C

2 papers

NM_003062.4

p.G373E

c.1118G>A

1 paper

NM_003062.4

p.D376H

c.1126G>C