Varaico: Literature-Extracted Genetic Variants

Gene:SLX4
Variant:p.I1421S

SLX4

607 papers

RefSeq Summary

This gene encodes a protein that functions as an assembly component of multiple structure-specific endonucleases. These endonuclease complexes are required for repair of specific types of DNA lesions ...

Pfam Domains

BTBaa 681–794UCSCBTB/POZ domain
Slx4aa 1753–1810UCSCSlx4 endonuclease

Gene Aliases

HGNC Name

SLX4 structure-specific endonuclease subunit

HGNC Previous Symbol

BTBD12

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_032444.4
p.I1421S
c.4262T>G
Surrounding Variants
1 paper
NM_032444.4
p.I1421fs
c.4261_4262fs
2 papers
NM_032444.4
p.I1421fs
c.4261_4262fs
4 papers
NM_032444.4
p.I1421F
c.4261A>T
2 papers
NM_032444.4
p.P1422A
c.4264C>G
5 papers
NM_032444.4
p.P1420insFs
c.4259dupC
1 paper
NM_032444.4
p.P1420fs
c.4258_4259fs
1 paper
NM_032444.4
p.P1419L
c.4256C>T
1 paper
NM_032444.4
p.S1417R
c.4251T>G
1 paper
NM_032444.4
p.S1417R
c.4251T>A
1 paper
NM_032444.4
p.D1425N
c.4273G>A
1 paper
NM_032444.4
p.S1417R
c.4249A>C
1 paper
NM_032444.4
p.W1428*
c.4283G>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."