Varaico: Literature-Extracted Genetic Variants

Gene:SLX4
Variant:p.E456Splc

SLX4

607 papers

RefSeq Summary

This gene encodes a protein that functions as an assembly component of multiple structure-specific endonucleases. These endonuclease complexes are required for repair of specific types of DNA lesions ...

Pfam Domains

BTBaa 681–794UCSCBTB/POZ domain
Slx4aa 1753–1810UCSCSlx4 endonuclease

Gene Aliases

HGNC Name

SLX4 structure-specific endonuclease subunit

HGNC Previous Symbol

BTBD12

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_032444.4
p.E456Splc
c.1367-2A>G
Surrounding Variants
1 paper
NM_032444.4
p.E456*
c.1366G>T
1 paper
NM_032444.4
p.E456K
c.1366G>A
3 papers
NM_032444.4
p.N457K
c.1371T>G
3 papers
NM_032444.4
p.N457K
c.1371T>A
9 papers
NM_032444.4
p.K458E
c.1372A>G
4 papers
NM_032444.4
p.P465L
c.1394C>T
2 papers
NM_032444.4
p.V466G
c.1397T>G
1 paper
NM_032444.4
p.S467insFs
c.1399_1400insC
1 paper
NM_032444.4
p.P468P
c.1404C>A
1 paper
NM_032444.4
p.P469L
c.1406C>T
1 paper
NM_032444.4
p.P469insFs
c.1406_1407insC
2 papers
NM_032444.4
p.P469fs
c.1405_1406fs
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."