Varaico: Literature-Extracted Genetic Variants

Gene:SMO
Variant:p.A406delFs

SMO

1,034 papers

RefSeq Summary

The protein encoded by this gene is a G protein-coupled receptor that interacts with the patched protein, a receptor for hedgehog proteins. The encoded protein tranduces signals to other proteins afte...

Pfam Domains

Fzaa 70–178UCSCFz domain
Frizzledaa 221–552UCSCFrizzled/Smoothened family membrane region

Gene Aliases

HGNC Name

smoothened, frizzled class receptor

HGNC Previous Symbol

SMOH

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_005631.5
p.A406delFs
c.1217delC
Surrounding Variants
1 paper
NM_005631.5
p.A406T
c.1216G>A
1 paper
NM_005631.5
p.A406P
c.1216G>C
1 paper
NM_005631.5
p.A406fs
c.1216_1217fs
2 papers
NM_005631.5
p.P407A
c.1219C>G
1 paper
NM_005631.5
p.L405L
c.1213C>T
1 paper
NM_005631.5
p.P407insFs
c.1220_1221insT
1 paper
NM_005631.5
p.P407L
c.1220C>T
1 paper
NM_005631.5
p.I408L
c.1222A>C
7 papers
NM_005631.5
p.I408V
c.1222A>G
14 papers
NM_005631.5
p.V404M
c.1210G>A
2 papers
NM_005631.5
p.F403L
c.1209C>A
2 papers
NM_005631.5
p.F403L
c.1209C>G
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."