sterol O-acyltransferase 1

sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1

acyl-Coenzyme A: cholesterol acyltransferase

Sterol O-acyltransferase 1

Acyl-coenzyme A:cholesterol acyltransferase 1

Cholesterol acyltransferase 1

ACAT-1

MBOAT, membrane-bound O-acyltransferase family

The protein encoded by this gene belongs to the acyltransferase family. It is located in the endoplasmic reticulum, and catalyzes the formation of fatty acid-cholesterol esters. This gene has been implicated in the formation of beta-amyloid and atherosclerotic plaques by controlling the equilibrium between free cholesterol and cytoplasmic cholesteryl esters. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2011].

Varaico: Literature-Extracted Genetic Variants

SOAT1

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Previous Name