Varaico: Literature-Extracted Genetic Variants

SOCS4

25 papers

RefSeq Summary

The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS), also known as STAT-induced STAT inhibitor (SSI), ...

Pfam Domains

SOCSaa 58–113UCSCSuppressor of cytokine signalling

SH2aa 286–364UCSCSH2 domain

SOCS_boxaa 385–420UCSCSOCS box

Gene Aliases

HGNC Name

suppressor of cytokine signaling 4

HGNC Previous Name

suppressor of cytokine signaling 7

Papers

RefSeq ID

Protein change

DNA change

1–12 of 20 variants

3 papers

NM_199421.2

p.T266M

c.797C>T

2 papers

NM_199421.2

p.G54S

c.160G>A

1 paper

NM_199421.2

p.G29S

c.85G>A

1 paper

NM_199421.2

p.G29D

c.86G>A

1 paper

NM_199421.2

p.V60fs

c.178_179fs

1 paper

NM_199421.2

p.V60delFs

c.179delT

1 paper

NM_199421.2

p.H69Y

c.205C>T

1 paper

NM_199421.2

p.R178*

c.532C>T

1 paper

NM_199421.2

p.D201N

c.601G>A

1 paper

NM_199421.2

p.L237Fs

c.711delinsAAGGAAGGFs

1 paper

NM_199421.2

p.C238fs

c.712_713fs

1 paper

NM_199421.2

p.Y270C

c.809A>G