Varaico: Literature-Extracted Genetic Variants

SOCS4

25 papers

RefSeq Summary

The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS), also known as STAT-induced STAT inhibitor (SSI), ...

Pfam Domains

SOCSaa 58–113UCSCSuppressor of cytokine signalling

SH2aa 286–364UCSCSH2 domain

SOCS_boxaa 385–420UCSCSOCS box

Gene Aliases

HGNC Name

suppressor of cytokine signaling 4

HGNC Previous Name

suppressor of cytokine signaling 7

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_199421.2

p.C238fs

c.712_713fs

Surrounding Variants

1 paper

NM_199421.2

p.L237Fs

c.711delinsAAGGAAGGFs

3 papers

NM_199421.2

p.T266M

c.797C>T

1 paper

NM_199421.2

p.Y270C

c.809A>G

1 paper

NM_199421.2

p.D201N

c.601G>A

1 paper

NM_199421.2

p.P276S

c.826C>T

1 paper

NM_199421.2

p.N282S

c.845A>G

1 paper

NM_199421.2

p.R178*

c.532C>T

1 paper

NM_199421.2

p.R329H

c.986G>A

1 paper

NM_199421.2

p.W338C

c.1014G>C

1 paper

NM_199421.2

p.W338C

c.1014G>T

1 paper

NM_199421.2

p.T358I

c.1073C>T

1 paper

NM_199421.2

p.L361Q

c.1082T>A