Varaico: Literature-Extracted Genetic Variants

SOCS5

46 papers

RefSeq Summary

The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS) family, also known as STAT-induced STAT inhibitor ...

Pfam Domains

SOCSaa 145–197UCSCSuppressor of cytokine signalling

SH2aa 381–459UCSCSH2 domain

SOCS_boxaa 480–515UCSCSOCS box

Gene Aliases

HGNC Name

suppressor of cytokine signaling 5

HGNC Alias Symbols

KIAA0671; SOCS-5; CIS6; CISH6; Cish5

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_144949.3

p.G173*

c.517G>T

Surrounding Variants

1 paper

NM_144949.3

p.L177V

c.529C>G

1 paper

NM_144949.3

p.S198fs

c.592_593fs

1 paper

NM_144949.3

p.K205R

c.614A>G

1 paper

NM_144949.3

p.S211A

c.631T>G

1 paper

NM_144949.3

p.D225H

c.673G>C

1 paper

NM_144949.3

p.D112A

c.335A>C

1 paper

NM_144949.3

p.D99delFs

c.296delA

1 paper

NM_144949.3

p.T249T

c.747A>G

1 paper

NM_144949.3

p.E95fs

c.283_284fs

1 paper

NM_144949.3

p.E260G

c.779A>G

1 paper

NM_144949.3

p.A83V

c.248C>T

1 paper

NM_144949.3

p.C82G

c.244T>G