Varaico: Literature-Extracted Genetic Variants

SOCS5

46 papers

RefSeq Summary

The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS) family, also known as STAT-induced STAT inhibitor ...

Pfam Domains

SOCSaa 145–197UCSCSuppressor of cytokine signalling

SH2aa 381–459UCSCSH2 domain

SOCS_boxaa 480–515UCSCSOCS box

Gene Aliases

HGNC Name

suppressor of cytokine signaling 5

HGNC Alias Symbols

KIAA0671; SOCS-5; CIS6; CISH6; Cish5

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_144949.3

p.I474M

c.1422A>G

Surrounding Variants

1 paper

NM_144949.3

p.S483N

c.1448G>A

1 paper

NM_144949.3

p.L484P

c.1451T>C

2 papers

NM_144949.3

p.S464L

c.1391C>T

1 paper

NM_144949.3

p.C488F

c.1463G>T

1 paper

NM_144949.3

p.K460E

c.1378A>G

1 paper

NM_144949.3

p.R489H

c.1466G>A

1 paper

NM_144949.3

p.E457V

c.1370A>T

1 paper

NM_144949.3

p.T496I

c.1487C>T

1 paper

NM_144949.3

p.L504L

c.1512C>A

1 paper

NM_144949.3

p.A441V

c.1322C>T

1 paper

NM_144949.3

p.A441T

c.1321G>A

1 paper

NM_144949.3

p.M509V

c.1525A>G