Varaico: Literature-Extracted Genetic Variants

Gene:SOCS6
Variant:p.E249*

SOCS6

37 papers

RefSeq Summary

The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (...

Pfam Domains

SH2aa 384–461UCSCSH2 domain
SOCS_boxaa 496–531UCSCSOCS box

Gene Aliases

HGNC Name

suppressor of cytokine signaling 6

HGNC Alias Symbols

CIS4; SSI4; HSPC060; STATI4; STAI4; Cish4

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_004232.4
p.E249*
c.745G>T
Surrounding Variants
1 paper
NM_004232.4
p.D243Y
c.727G>T
1 paper
NM_004232.4
p.G259A
c.776G>C
1 paper
NM_004232.4
p.M231L
c.691A>C
1 paper
NM_004232.4
p.M231L
c.691A>T
1 paper
NM_004232.4
p.A276T
c.826G>A
1 paper
NM_004232.4
p.T293M
c.878C>T
1 paper
NM_004232.4
p.H197Y
c.589C>T
1 paper
NM_004232.4
p.K192T
c.575A>C
1 paper
NM_004232.4
p.P312Q
c.935C>A
1 paper
NM_004232.4
p.H176H
c.528C>T
1 paper
NM_004232.4
p.P164L
c.491C>T
1 paper
NM_004232.4
p.D347Y
c.1039G>T
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