Varaico: Literature-Extracted Genetic Variants

SPARC

256 papers

RefSeq Summary

This gene encodes a cysteine-rich acidic matrix-associated protein. The encoded protein is required for the collagen in bone to become calcified but is also involved in extracellular matrix synthesis ...

Pfam Domains

FOLNaa 72–93UCSCFollistatin/Osteonectin-like EGF domain

Kazal_1aa 95–149UCSCKazal-type serine protease inhibitor domain

SPARC_Ca_bdgaa 152–289UCSCSecreted protein acidic and rich in cysteine Ca binding region

Gene Aliases

HGNC Name

secreted protein acidic and cysteine rich

HGNC Previous Symbol

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003118.4

p.F7C

c.20T>G

Surrounding Variants

2 papers

NM_003118.4

p.F7S

c.20T>C

1 paper

NM_003118.4

p.F7Y

c.20T>A

1 paper

NM_003118.4

p.F7V

c.19T>G

1 paper

NM_003118.4

p.L8H

c.23T>A

1 paper

NM_003118.4

p.F6I

c.16T>A

1 paper

NM_003118.4

p.I5I

c.15C>T

1 paper

NM_003118.4

p.W4*

c.12G>A

1 paper

NM_003118.4

p.W4delFs

c.10delA

1 paper

NM_003118.4

p.L11L

c.31C>T

1 paper

NM_003118.4

p.A3A

c.9C>T

1 paper

NM_003118.4

p.L11Q

c.32T>A

1 paper

NM_003118.4

p.A3D

c.8C>A