Varaico: Literature-Extracted Genetic Variants

SPDYE6

18 papers

RefSeq Summary

This gene encodes a cell cycle regulatory protein which plays an important role in cell cycle progression by binding and activating cyclin-dependent kinases. The encoded protein belongs to a family of...

Pfam Domains

Spy1aa 194–310UCSCCell cycle regulatory protein

Spy1aa 347–398UCSCCell cycle regulatory protein

Gene Aliases

HGNC Name

speedy/RINGO cell cycle regulator family member E6

HGNC Previous Name

speedy homolog E6 (Xenopus laevis)

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001146210.4

p.E166V

c.497A>T

Surrounding Variants

1 paper

NM_001146210.4

p.P135fs

c.403_404fs

1 paper

NM_001146210.4

p.L106L

c.318G>A

1 paper

NM_001146210.4

p.A231V

c.692C>T

1 paper

NM_001146210.4

p.E5Q

c.13G>C

1 paper

NM_001146210.4

p.R278L

c.833G>T

1 paper

NM_001146210.4

p.L284F

c.850C>T

1 paper

NM_001146210.4

p.R285H

c.854G>A

1 paper

NM_001146210.4

p.G292C

c.874G>T

6 papers

NM_001146210.4

p.P297L

c.890C>T

1 paper

NM_001146210.4

p.R305C

c.913C>T

1 paper

NM_001146210.4

p.R335C

c.1003C>T

1 paper

NM_001146210.4

p.H337R

c.1010A>G