Varaico: Literature-Extracted Genetic Variants

Gene:SPHK2
Variant:p.G26A

SPHK2

52 papers

RefSeq Summary

This gene encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate. Sphingosine 1-phosphate mediates many cellular processes includi...

Pfam Domains

DAGK_cataa 182–321UCSCDiacylglycerol kinase catalytic domain
YegS_Caa 532–644UCSCYegS C-terminal NAD kinase beta sandwich-like domain

Gene Aliases

HGNC Name

sphingosine kinase 2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_020126.5
p.G26A
c.77G>C
Surrounding Variants
1 paper
NM_020126.5
p.L31L
c.93G>T
1 paper
NM_020126.5
p.V32V
c.96C>T
1 paper
NM_020126.5
p.E18K
c.52G>A
1 paper
NM_020126.5
p.P41S
c.121C>T
1 paper
NM_020126.5
p.P41Fs
c.121delinsTTFs
1 paper
NM_020126.5
p.P41L
c.122C>T
1 paper
NM_020126.5
p.T48I
c.143C>T
1 paper
NM_020126.5
p.L50L
c.150C>T
1 paper
NM_020126.5
p.H52Y
c.154C>T
1 paper
NM_020126.5
p.R78Q
c.233G>A
1 paper
NM_020126.5
p.R80C
c.238C>T
1 paper
NM_020126.5
p.R80H
c.239G>A
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."