Varaico: Literature-Extracted Genetic Variants

Gene:SPRED1
Variant:p.Y261D

SPRED1

244 papers

RefSeq Summary

The protein encoded by this gene is a member of the Sprouty family of proteins and is phosphorylated by tyrosine kinase in response to several growth factors. The encoded protein can act as a homodime...

Pfam Domains

WH1aa 10–120UCSCWH1 domain
Sproutyaa 332–441UCSCSprouty protein (Spry)

Gene Aliases

HGNC Name

sprouty related EVH1 domain containing 1

HGNC Alias Symbols

FLJ33903; PPP1R147; SPRED-1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_152594.3
p.Y261D
c.781T>G
Surrounding Variants
1 paper
NM_152594.3
p.Y261H
c.781T>C
2 papers
NM_152594.3
p.R262*
c.784A>T
1 paper
NM_152594.3
p.Y258C
c.773A>G
1 paper
NM_152594.3
p.R257S
c.769C>A
3 papers
NM_152594.3
p.R257C
c.769C>T
1 paper
NM_152594.3
p.D265H
c.793G>C
1 paper
NM_152594.3
p.D265insFs
c.794dupA
1 paper
NM_152594.3
p.D265fs
c.793_794fs
3 papers
NM_152594.3
p.M266delFs
c.796_797delAT
3 papers
NM_152594.3
p.R256H
c.767G>A
1 paper
NM_152594.3
p.M266fs
c.796_797fs
2 papers
NM_152594.3
p.M266V
c.796A>G
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."