Varaico: Literature-Extracted Genetic Variants

Gene:SPRY4
Variant:p.T100M

SPRY4

97 papers

RefSeq Summary

This gene encodes a member of a family of cysteine- and proline-rich proteins. The encoded protein is an inhibitor of the receptor-transduced mitogen-activated protein kinase (MAPK) signaling pathway....

Pfam Domains

Sproutyaa 164–276UCSCSprouty protein (Spry)

Gene Aliases

HGNC Name

sprouty RTK signaling antagonist 4

HGNC Previous Name

sprouty homolog 4 (Drosophila)

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
3 papers
NM_030964.5
p.T100M
c.299C>T
NM_001127496.3
p.T77M
c.230C>T
Surrounding Variants
1 paper
NM_001127496.3
p.T77T
c.231G>A
1 paper
NM_001127496.3
p.P76fs
c.226_227fs
1 paper
NM_001127496.3
p.P76delFs
c.227delG
1 paper
NM_001127496.3
p.A75delFs
c.223_224delGC
1 paper
NM_001127496.3
p.R80G
c.238C>G
1 paper
NM_001127496.3
p.R80H
c.239G>A
1 paper
NM_001127496.3
p.R80fs
c.238_239fs
1 paper
NM_001127496.3
p.E73*
c.217G>T
1 paper
NM_001127496.3
p.D82Y
c.244G>T
2 papers
NM_030964.5
p.D105N
c.313G>A
NM_001127496.3
p.D82N
c.244G>A
1 paper
NM_001127496.3
p.D84V
c.251A>T
1 paper
NM_001127496.3
p.G70R
c.208G>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."