serine palmitoyltransferase small subunit A

C14orf147

ssSPTa

chromosome 14 open reading frame 147

serine palmitoyltransferase, small subunit A

small subunit of serine palmitoyltransferase A

Serine palmitoyltransferase small subunit A

Small subunit of serine palmitoyltransferase A

Small subunit of serine palmitoyltransferase-like

Serine palmitoyltransferase (SPT; EC 2.3.1.50) catalyzes the first committed and rate-limiting step in sphingolipid biosynthesis. SSSPTA is a small SPT subunit that stimulates SPT activity and confers acyl-CoA preference to the SPT catalytic heterodimer of SPTLC1 (MIM 605712) and either SPTLC2 (MIM 605713) or SPTLC3 (MIM 611120) (Han et al., 2009 [PubMed 19416851]).[supplied by OMIM, Nov 2010].

Varaico: Literature-Extracted Genetic Variants

SPTSSA

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Previous Symbol