Varaico: Literature-Extracted Genetic Variants

SRC

787 papers

RefSeq Summary

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is...

Pfam Domains

SH3_1aa 90–137UCSCSH3 domain

SH2aa 151–233UCSCSH2 domain

PK_Tyr_Ser-Thraa 270–519UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

SRC proto-oncogene, non-receptor tyrosine kinase

HGNC Previous Symbol

SRC1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_198291.3

p.P20_G26insFs

c.59_77dup19

Surrounding Variants

2 papers

NM_198291.3

p.P20A

c.58C>G

2 papers

NM_198291.3

p.P20H

c.59C>A

1 paper

NM_198291.3

p.E19G

c.56A>G

1 paper

NM_198291.3

p.P20P

c.60C>G

1 paper

NM_198291.3

p.P20P

c.60C>T

2 papers

NM_198291.3

p.A21T

c.61G>A

1 paper

NM_198291.3

p.E19Q

c.55G>C

1 paper

NM_198291.3

p.A21D

c.62C>A

1 paper

NM_198291.3

p.E22K

c.64G>A

1 paper

NM_198291.3

p.S17N

c.50G>A

1 paper

NM_198291.3

p.S17T

c.50G>C

1 paper

NM_198291.3

p.N23D

c.67A>G