Varaico: Literature-Extracted Genetic Variants

SRC

787 papers

RefSeq Summary

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is...

Pfam Domains

SH3_1aa 90–137UCSCSH3 domain

SH2aa 151–233UCSCSH2 domain

PK_Tyr_Ser-Thraa 270–519UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

SRC proto-oncogene, non-receptor tyrosine kinase

HGNC Previous Symbol

SRC1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_198291.3

p.D45insFs

c.133_134ins10

Surrounding Variants

2 papers

NM_198291.3

p.D45N

c.133G>A

1 paper

NM_198291.3

p.D45Y

c.133G>T

1 paper

NM_198291.3

p.D45fs

c.133_134fs

1 paper

NM_198291.3

p.D45A

c.134A>C

1 paper

NM_198291.3

p.A44_D45insFs

c.132_133ins7

1 paper

NM_198291.3

p.A44D

c.131C>A

1 paper

NM_198291.3

p.D45E

c.135C>A

1 paper

NM_198291.3

p.A44G

c.131C>G

1 paper

NM_198291.3

p.D45E

c.135C>G

1 paper

NM_198291.3

p.A44T

c.130G>A

1 paper

NM_198291.3

p.G46R

c.136G>C

2 papers

NM_198291.3

p.G46D

c.137G>A