Varaico: Literature-Extracted Genetic Variants

SRC

787 papers

RefSeq Summary

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is...

Pfam Domains

SH3_1aa 90–137UCSCSH3 domain

SH2aa 151–233UCSCSH2 domain

PK_Tyr_Ser-Thraa 270–519UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

SRC proto-oncogene, non-receptor tyrosine kinase

HGNC Previous Symbol

SRC1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_198291.3

p.G49C

c.145G>T

Surrounding Variants

1 paper

NM_198291.3

p.G49R

c.145G>C

2 papers

NM_198291.3

p.G49D

c.146G>A

2 papers

NM_198291.3

p.R48S

c.142C>A

1 paper

NM_198291.3

p.R48G

c.142C>G

3 papers

NM_198291.3

p.R48C

c.142C>T

1 paper

NM_198291.3

p.H47Q

c.141C>A

1 paper

NM_198291.3

p.P50H

c.149C>A

1 paper

NM_198291.3

p.H47Q

c.141C>G

1 paper

NM_198291.3

p.P50R

c.149C>G

1 paper

NM_198291.3

p.H47P

c.140A>C

2 papers

NM_198291.3

p.S51R

c.151A>C

1 paper

NM_198291.3

p.H47Y

c.139C>T