Varaico: Literature-Extracted Genetic Variants

SRC

787 papers

RefSeq Summary

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is...

Pfam Domains

SH3_1aa 90–137UCSCSH3 domain

SH2aa 151–233UCSCSH2 domain

PK_Tyr_Ser-Thraa 270–519UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

SRC proto-oncogene, non-receptor tyrosine kinase

HGNC Previous Symbol

SRC1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_198291.3

p.E60A

c.179A>C

Surrounding Variants

1 paper

NM_198291.3

p.E60K

c.178G>A

1 paper

NM_198291.3

p.E60D

c.180G>C

1 paper

NM_198291.3

p.E60D

c.180G>T

1 paper

NM_198291.3

p.P61S

c.181C>T

2 papers

NM_198291.3

p.P61H

c.182C>A

1 paper

NM_198291.3

p.A59G

c.176C>G

1 paper

NM_198291.3

p.A59V

c.176C>T

4 papers

NM_198291.3

p.A59T

c.175G>A

1 paper

NM_198291.3

p.K62E

c.184A>G

1 paper

NM_198291.3

p.K62R

c.185A>G

1 paper

NM_198291.3

p.A58V

c.173C>T

1 paper

NM_198291.3

p.A58T

c.172G>A