Varaico: Literature-Extracted Genetic Variants

SRC

787 papers

RefSeq Summary

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is...

Pfam Domains

SH3_1aa 90–137UCSCSH3 domain

SH2aa 151–233UCSCSH2 domain

PK_Tyr_Ser-Thraa 270–519UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

SRC proto-oncogene, non-receptor tyrosine kinase

HGNC Previous Symbol

SRC1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_198291.3

p.E169G

c.506A>G

Surrounding Variants

1 paper

NM_198291.3

p.A168G

c.503C>G

1 paper

NM_198291.3

p.N170K

c.510C>A

1 paper

NM_198291.3

p.N170K

c.510C>G

2 papers

NM_198291.3

p.A168T

c.502G>A

1 paper

NM_198291.3

p.A168P

c.502G>C

1 paper

NM_198291.3

p.P171A

c.511C>G

1 paper

NM_198291.3

p.N167K

c.501T>A

1 paper

NM_198291.3

p.N167K

c.501T>G

4 papers

NM_198291.3

p.P171L

c.512C>T

1 paper

NM_198291.3

p.N167H

c.499A>C

1 paper

NM_198291.3

p.R172*

c.514A>T

2 papers

NM_198291.3

p.R172K

c.515G>A