Varaico: Literature-Extracted Genetic Variants

SRC

787 papers

RefSeq Summary

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is...

Pfam Domains

SH3_1aa 90–137UCSCSH3 domain

SH2aa 151–233UCSCSH2 domain

PK_Tyr_Ser-Thraa 270–519UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

SRC proto-oncogene, non-receptor tyrosine kinase

HGNC Previous Symbol

SRC1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

4 papers

NM_198291.3

p.V177M

c.529G>A

Surrounding Variants

2 papers

NM_198291.3

p.L176F

c.526C>T

1 paper

NM_198291.3

p.R178*

c.532C>T

1 paper

NM_198291.3

p.F175F

c.525C>T

1 paper

NM_198291.3

p.R178L

c.533G>T

1 paper

NM_198291.3

p.E179G

c.536A>G

1 paper

NM_198291.3

p.E179D

c.537A>C

1 paper

NM_198291.3

p.E179D

c.537A>T

1 paper

NM_198291.3

p.T174N

c.521C>A

1 paper

NM_198291.3

p.T174A

c.520A>G

1 paper

NM_198291.3

p.S180N

c.539G>A

1 paper

NM_198291.3

p.G173V

c.518G>T

2 papers

NM_198291.3

p.R172K

c.515G>A