Varaico: Literature-Extracted Genetic Variants

SRC

787 papers

RefSeq Summary

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is...

Pfam Domains

SH3_1aa 90–137UCSCSH3 domain

SH2aa 151–233UCSCSH2 domain

PK_Tyr_Ser-Thraa 270–519UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

SRC proto-oncogene, non-receptor tyrosine kinase

HGNC Previous Symbol

SRC1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_198291.3

p.A374T

c.1120G>A

Surrounding Variants

1 paper

NM_198291.3

p.S375L

c.1124C>T

1 paper

NM_198291.3

p.Q372_I373Splc

c.1117-1G>C

1 paper

NM_198291.3

p.G376D

c.1127G>A

1 paper

NM_198291.3

p.M377insFs

c.1129dupA

1 paper

NM_198291.3

p.M377R

c.1130T>G

1 paper

NM_198291.3

p.A378V

c.1133C>T

2 papers

NM_198291.3

p.Y379*

c.1137C>A

2 papers

NM_198291.3

p.Y379*

c.1137C>G

2 papers

NM_198291.3

p.V380M

c.1138G>A

4 papers

NM_198291.3

p.E381K

c.1141G>A

1 paper

NM_198291.3

p.E381G

c.1142A>G

2 papers

NM_198291.3

p.R382W

c.1144C>T