Varaico: Literature-Extracted Genetic Variants

SRC

787 papers

RefSeq Summary

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is...

Pfam Domains

SH3_1aa 90–137UCSCSH3 domain

SH2aa 151–233UCSCSH2 domain

PK_Tyr_Ser-Thraa 270–519UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

SRC proto-oncogene, non-receptor tyrosine kinase

HGNC Previous Symbol

SRC1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_198291.3

p.N400T

c.1199A>C

Surrounding Variants

1 paper

NM_198291.3

p.N400K

c.1200C>A

1 paper

NM_198291.3

p.N400K

c.1200C>G

1 paper

NM_198291.3

p.L401V

c.1201C>G

1 paper

NM_198291.3

p.E399K

c.1195G>A

2 papers

NM_198291.3

p.G398R

c.1192G>A

2 papers

NM_198291.3

p.G398R

c.1192G>C

2 papers

NM_198291.3

p.C403Y

c.1208G>A

1 paper

NM_198291.3

p.L396P

c.1187T>C

1 paper

NM_198291.3

p.L396R

c.1187T>G

1 paper

NM_198291.3

p.I395M

c.1185C>G

1 paper

NM_198291.3

p.V405E

c.1214T>A

1 paper

NM_198291.3

p.A406V

c.1217C>T