Varaico: Literature-Extracted Genetic Variants

SRC

787 papers

RefSeq Summary

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is...

Pfam Domains

SH3_1aa 90–137UCSCSH3 domain

SH2aa 151–233UCSCSH2 domain

PK_Tyr_Ser-Thraa 270–519UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

SRC proto-oncogene, non-receptor tyrosine kinase

HGNC Previous Symbol

SRC1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_198291.3

p.R422Q

c.1265G>A

Surrounding Variants

1 paper

NM_198291.3

p.R422G

c.1264C>G

1 paper

NM_198291.3

p.A421A

c.1263G>T

1 paper

NM_198291.3

p.A421V

c.1262C>T

1 paper

NM_198291.3

p.A421T

c.1261G>A

1 paper

NM_198291.3

p.T420M

c.1259C>T

1 paper

NM_198291.3

p.G424D

c.1271G>A

2 papers

NM_198291.3

p.Y419F

c.1256A>T

2 papers

NM_198291.3

p.Y419N

c.1255T>A

1 paper

NM_198291.3

p.Y419ins2

c.1255_1256ins6

1 paper

NM_198291.3

p.E418K

c.1252G>A

1 paper

NM_198291.3

p.N417K

c.1251T>A

1 paper

NM_198291.3

p.N417K

c.1251T>G